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Research Matters

Genetic prediction of educational attainment: the important role of parental behaviour

By | Research Matters

Scientists are building powerful predictors of our educational attainment based on genetic information. These ‘polygenic scores’ measure the genetic load that individuals carry for a specific trait. Considered individually, genetic variants have tiny effects, but when these are added up into a polygenic score, they explain a considerable proportion of…

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Anxiety in the family

By | Research Matters

Yasmin [EDIT Lab PhD student] outlines our latest publication on anxiety symptoms in the family. Anxiety in parents is associated with anxiety in offspring, but it’s not yet clear how this happens. We conducted the first study to use a ‘genetically sensitive’ research design to examine the effects of mother,…

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Extracting stability gives a more powerful and heritable measure of emotional problems

By | Research Matters

This blog explains our latest publication in which we analysed Twins Early Development Study data on emotional problems across childhood and adolescence. Accurate assessment is difficult but essential if we are to understand the influences on emotional problems. We took advantage of longitudinal data (i.e. taken across time) to define…

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The largest genome-wide association study of depression was published last month. What did they find and what happens next?

By | Research Matters

Depression is a leading cause of disability worldwide, contributing considerably to early mortality. Despite significant efforts, the genetics underlying depression has been difficult to identify and there has been limited progress in developing new treatments. Last month the largest genome-wide association study of depression was published in Nature Genetics (1)….

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