The MOSAIC trial and Covid-19

Archive image: Unsplash, Klaudia Piaskowska

It has been a challenging couple of months for the MOSAIC team. In line with most non-COVID-19 clinical research in the UK, we have been unable to meet our participants face-to-face or recruit new participants since the mid-March. That doesn’t mean we haven’t been busy!

Our last day on the Guy’s campus, London Bridge, was on Tuesday March 17th. The start of that week was a flurry of office-based activity to ensure that the team could work effectively from home. The rest of the week was spent getting to grips with the new technology, and ways of working, needed to be able to work from our front room.

We have continued to keep in touch with participants actively enrolled on the trial. Although we haven’t been able to collect walk test data, we have been able to collect the rest of the questionnaire data required at 3 months and 6 months following the baseline visit. Participants have very kindly filled in questionnaires at home, and sent them back either via post or electronically. It’s been very rewarding to chat to participants on the phone and discover how they are spending lockdown, for instance, one has started Zumba classes in the front room!

We realise that lock-down has changed everyone’s lives. Mr Graham Fisher, one of our patient representatives, gave his perspective on how life under lockdown has changed his routine.

Mr Fisher said: “I am getting along very well. I am able to get out for shopping but trying to limit trips to one a week.

“My pattern of exercising has changed. Gone is my usual routine of driving for 15 minutes 2 or 3 times a week to a large park. But I am fortunate to have a small park 200 yards from home so I can do several laps there.”

More information and ideas about how to keep healthy at this time can be found on the Circulation Foundation website:

The team have also used this time to conduct interviews with participants who have completed the trial. Brittannia Volkmer has interviewed 30 participants and is now analysing them. This will tell us about the participants experience of the MOSAIC intervention and being on the trial. Thank you to everyone who took part in these interviews, your insights are very valuable.

Finally, Dr Julie Bieles has been analysing interviews, which we conducted with the physiotherapists that delivered the MOSAIC intervention. Analysis of these interviews will tell us what the physiotherapists thought about delivering MOSAIC and the training that they received, and also help us understand the techniques the physios found most useful to help them deliver intervention sessions.

Stay safe everyone!

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