Monthly Archives: July 2018

P is for Polygenic Risk Scores

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Nearly all human traits, such as height, weight, and intelligence, and common disorders like major depressive and anxiety disorders are polygenic. This means that variation in more than one gene (usually many genes) contributes to total genetic predisposition for a specific trait or disorder. Chris outlines how Polygenic Risk Scores…

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N for Neuroticism

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Neuroticism is a personality trait characterised by easily experiencing negative emotions. This A-Z blog offers some highlights of what is currently known about the genetic and environmental influences on neuroticism, as well as its overlap with and relevance for psychiatric disorders.

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M for Missing Heritability

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Decades of twin studies have yielded evidence of the heritability of many different traits. What we mean by this is the proportion of variation in a trait that can be explained by genetic differences between individuals. Research has moved towards identifying specific genetic variants associated with these traits through Genome-Wide…

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L for Loneliness

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Human beings are social species. We naturally interact and bond with other people. According to evolutionary theory, loneliness has played an important role in the survival of humans because connecting with others increases one’s chances of living (Cacioppo, Hawkley, et al., 2006). Still today, it seems that we feel lonely…

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